ADYNOVATE—A proven prophylaxis treatment that has twice-weekly dosing1
Treating your condition is not always easy. Life gets busy. For some people getting into a treatment routine can be helpful. ADYNOVATE has a simple twice-weekly dosing schedule so you treat on the same days each week.1 Ask your doctor whether a treatment like this could be right for you.
Dosing schedule
Here is an example of how you and your HCP may schedule your ADYNOVATE treatment.
These are examples of what an ADYNOVATE prophylaxis dosing schedule could look like. Your dosing schedule may be different. Always follow your dosing schedule as set by your healthcare provider.
Now that you understand the dosing schedule for ADYNOVATE, take a moment and learn about its safety profile.
Could ADYNOVATE mean one less infusion per week for you?
70% (69 out of 98) of adolescents and adults 12 years and older in a clinical study were able to reduce the frequency of prophylaxis dosing from their pre-study prophylaxis dosing regimen by 30% or more, which is approximately 1 fewer infusion per week. Talk to your doctor to learn what this could mean for you.2
SELECTED IMPORTANT RISK INFORMATION
What are possible side effects of ADYNOVATE?
The common side effects of ADYNOVATE are headache, diarrhea, rash, nausea, dizziness, and hives. These are not all the possible side effects with ADYNOVATE. Tell your HCP about any side effects that bother you or do not go away.
See Detailed Important Risk Information below.
How to reconstitute
What does reconstitution mean?
Reconstitution is the process of adding a diluent to a dry ingredient to make it a liquid. In this case, the powder form of ADYNOVATE is mixed with a diluent to create a clear liquid that's ready to infuse.1
Do not attempt to infuse yourself with ADYNOVATE unless you have been taught by your HCP or hemophilia treatment center.1
Watch the video below for step-by-step instructions on how to reconstitute ADYNOVATE with the BAXJECT III® Reconstitution System. You can also download the Instructions for Use, which includes troubleshooting information, here.
BAXJECT III Reconstitution System demonstration video (05:58)
For additional safety information, please see accompanying Full Prescribing Information and discuss with your HCP.
Benefits of the BAXJECT III Reconstitution System
Easy one-step activation for reconstituting ADYNOVATE with the BAXJECT III system1
Eliminates the need to disinfect, as vials are already assembled in the system housing (always ensure you work on a clean surface and wash your hands before reconstituting)1
Straightforward pooling process if more than 1 vial is needed—all ADYNOVATE can be drawn into the same syringe1
SELECTED IMPORTANT RISK INFORMATION
What important information do I need to know about ADYNOVATE?
You can have an allergic reaction to ADYNOVATE. Call your healthcare provider right away and stop treatment if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea or fainting.
Do not attempt to infuse yourself with ADYNOVATE unless you have been taught by your HCP or hemophilia center.
See Detailed Important Risk Information below.
Get better organized by tracking your bleeds and infusions all in one place.
“My mom and I decided to try ADYNOVATE because I'm striving for zero bleeds. I'm in charge of my treatment regimen, and infusing twice a week works well with my schedule.1 Since I have been on ADYNOVATE I haven't had any bleeds. Please keep in mind, though, that this is just my personal experience; yours may be different. That's why it's important to talk to your doctor to see if it's right for you.”
—Dylan, actual patient
Watch the Real People—Real Stories videos to see how ADYNOVATE is used in everyday life. Watch videos
Storage and handling
Available in seven dosage strengths, ADYNOVATE is a lyophilized powder packaged in single-use vials. The actual factor VIII potency is labeled on each ADYNOVATE vial so you can easily identify the dose. This may be more or less than the nominal vial potency/content.1
*sWFI = sterile Water For Injection
ADYNOVATE in a BAXJECT III® system is packaged with 2 mL and 5 mL of Sterile Water for Injection, one Terumo Microbore Infusion set (2 mL only), one full Prescribing Information insert, and one patient insert.1
How to store and handle ADYNOVATE1
Store ADYNOVATE in powder form at 2° to 8°C (36° to 46°F)
Do not freeze
ADYNOVATE may be stored at room temperature not to exceed 30°C (86°F) for a period of up to 3 months not to exceed the expiration date
After storage at room temperature, do not return the product to the refrigerator
Do not use beyond expiration date printed on the carton or vial
Store vials in their original box and protect from extreme light exposure
After reconstitution, do not refrigerate the solution. Use the reconstituted solution immediately or within 3 hours after reconstitution. Discard any remaining solution
Tailored treatment
The myPKFiT® mobile app is designed to help you track infusions, bleeds, and estimated FVIII levels.
Do not use ADYNOVATE if you are allergic to mice or hamster protein or are allergic to any ingredients in ADYNOVATE or ADVATE® [Antihemophilic Factor (Recombinant)]. Tell your HCP if you are pregnant or breastfeeding because ADYNOVATE may not be right for you.
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What does reconstitution mean?
Download bleed and infusion tracker worksheet
