ADYNOVATE is an injectable medicine that is used to help treat and control bleeding in children and adults with hemophilia A. ADYNOVATE is not used to treat von Willebrand disease.
Bleed control when it matters
Having a surgical procedure is a serious matter, and when you're living with hemophilia A, it can be even more so. That's why it's important to speak with your healthcare team about making a plan, that includes what's happening before, during, and after your surgery.
A study evaluated bleed control in surgical procedures for patients with severe hemophilia A using ADYNOVATE. 21 people participated in a total of 21 major surgeries and 5 minor surgeries.1,2
Bleed control was rated as Excellent in surgical procedures studied with ADYNOVATE
In surgical procedures, what does 'Excellent' mean?
An EXCELLENT rating means the blood loss during surgery was less than or equal to expected with the same type of procedure performed on a patient without hemophilia A.1
In the phase 3, multicenter, prospective, open-label, uncontrolled surgery study, 21 major surgical procedures and 5 minor surgeries were performed in 21 subjects.1,2
The primary endpoint was the evaluation during and after surgery of the hemostatic efficacy of ADYNOVATE in patients with severe hemophilia A.1,2
Using a 4-point scale of Excellent, Good, Fair, and None, surgeons evaluated the hemostatic efficacy of ADYNOVATE when used in a surgical environment.2
Excellent rating (for 24 surgeries that could be assessed)1
What is hemostatic?
A hemostatic agent is a product used to aid the process of preventing or stopping a bleed.
SELECTED IMPORTANT RISK INFORMATION
What important information do I need to know about ADYNOVATE?
You can have an allergic reaction to ADYNOVATE. Call your healthcare provider right away and stop treatment if you get a rash or hives, itching, tightness of the throat, chest pain or tightness, difficulty breathing, lightheadedness, dizziness, nausea or fainting.
Do not attempt to infuse yourself with ADYNOVATE unless you have been taught by your HCP or hemophilia center.
See Detailed Important Risk Information below.
Learn about the safety information and side effects of treatment with ADYNOVATE
Do not use ADYNOVATE if you are allergic to mice or hamster protein or are allergic to any ingredients in ADYNOVATE or ADVATE® [Antihemophilic Factor (Recombinant)]. Tell your HCP if you are pregnant or breastfeeding because ADYNOVATE may not be right for you.